Karlsruhe Institute of Technology (KIT) Germany

KIT.jpg  Leader: Urban Liebel
Brief description of the organisation: On October 01, 2009, the Karlsruhe Institute of Technology (KIT) was founded by a merger of Forschungszentrum Karlsruhe and Universität Karlsruhe. The basis was the KIT Merger Act that was adopted unanimously by the Baden-Württemberg state parliament in July 2009. KIT bundles the missions of both precursory institutions: A university of the state of Baden-Wuerttemberg with teaching and research tasks and a large-scale research institution of the Helmholtz Association conducting program-oriented provident research on behalf of the Federal Republic of Germany. Within these missions, KIT is operating along the three strategic fields of action of research, teaching, and innovation. With roundabout 8000 employees and an annual budget of about EUR 700 million, one of the largest research and teaching institutions worldwide is established in Karlsruhe. It has the potential to assume a top position worldwide in selected fields of research.
The objective: KIT will become an institution of top research and excellent scientific education as well as a prominent location of academic life, life-long learning, comprehensive advanced training, unrestricted exchange of know-how, and sustainable innovation culture.

Main tasks attributed to the project: High Throughput Screening of cis-regulatory elements in zebrafish embryos

Previous experience relevant to the tasks: Dr Urban Liebel studied biology and electronic engineering. He has been group leader in the ITG since 2007. Previously, he worked as a postdoc/scientific officer in the EMBL Heidelberg - Mitocheck project group. His group is experienced in the development of High content Screening platforms, image analysis and bioinformatic data integration.

Selected recent publications:
  • U Liebel, V Starkuviene, H Erfle, JC Simpson, R Pepperkok, A Microscope-Based Screening Platform For Large-Scale Functional Protein Analysis In Intact Cells. FEBS Letters 2003 Nov 20;554(3):394-8
  • B Neumann (#), M Held (#), U Liebel (#), H Erfle (#), P Rogers, R Pepperkok, J Ellenberg (#) = equal contribution, High-Throughput Screening By Time-Lapse Imaging Of Live Human Cells, Nat Methods. 2006 May;3(5):385-90.
  • U Liebel, B Kindler, R Pepperkok, Harvester: A Fast Meta Search Engine Of Human Protein Resources, Bioinformatics, Volume 20, Number 12, 12 August 2004 , pp. 1962-1963(2).
  • V Starkuviene (#), U Liebel (#), J Simpson, H Erfle, Stefan Wiemann and Rainer Pepperkok # = equal contribution, High-Content Screening Microscopy Identifies Novel Proteins With a Putative Role in Secretory membrane traffic, Genome Res. 14:1948-1956, 2004

Selected Patents Relevant To This Proposal:
  • Autofocussing System for Microscope Systems U Liebel - Wo Patent Wo/2006/097,123, 2006 European Molecular Biology Laboratory [De/De]; Meyerhofstrasse 1, 69117
  • Sample Carrier And A Microscope Structure U Liebel, R Pepperkok, S Winkler, H Schaar, Wo Patent Wo/2005/032,718, 2005 European Molecular Biology Laboratory [De/De]; Meyerhofstrasse 1, 69117 Heidelberg (De) (All Except Us).

Website: http://www.kit.edu